Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity

Julien Bertrand (1, 2, 3) , Rachel Marion-Letellier (1, 2, 3) , Saïda Azhar (1, 2, 3) , Philippe Chan (4, 2, 3) , Romain Legrand (1, 2, 3) , Alexis Goichon (1, 2, 3) , Ibtissem Ghouzali (1, 2, 3) , Moutaz Aziz (5) , David Vaudry (6, 2, 4, 3) , Guillaume Savoye (7, 1, 2, 3) , Pierre Déchelotte (8, 1, 2, 3) , Moïse Coëffier (1, 8, 2, 3)

1 ADEN - Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau
2 IRIB - Institute for Research and Innovation in Biomedicine
3 UNIROUEN - Université de Rouen Normandie
4 Plate-forme de Protéomique PISSARO
5 Service d'Anatomie et Cytologie Pathologique [CHU Rouen]
6 DC2N - Différenciation et communication neuronale et neuroendocrine
7 Service d'Hépato-Gastroentérologie [CHU Rouen]
8 Service de nutrition [CHU Rouen]

Domains: Life Sciences [q-bio]; Food and Nutrition; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Biochemistry [q-bio.BM]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Genomics [q-bio.GN]; Life Sciences [q-bio]; Human health and pathology; Life Sciences [q-bio]; Human health and pathology; Hépatology and Gastroenterology

Julien Bertrand, Rachel Marion-Letellier, Saïda Azhar, Philippe Chan, Romain Legrand, et al.. Glutamine enema regulates colonic ubiquitinated proteins but not proteasome activities during TNBS-induced colitis leading to increased mitochondrial activity. Proteomics, 2015, 15 (13), pp.2198-2210. ⟨10.1002/pmic.201400304⟩. ⟨hal-01958774⟩