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Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil

Olivier Neckebrock Laurent Courvoisier 1 Stephanie Graf Gilles Serrure Gerard Coquerel 1 Sebastien Rose Christine Besselievre Franck Mallet 1 Adriaan Van Langevelde
1 SMS - Sciences et Méthodes Séparatives
Abstract : The invention relates to a process for the preparation of crystalline forms of the optical enantiomers of modafinil, comprising stages comprising: i) dissolving one of the optical enantiomers of modafinil in a solvent other than ethanol, ii) crystallising the modafinil enantiomer, iii) recovering the crystalline form of the modafinil enantiomer so obtained. The invention also relates to a process for the preparation of the optical enantiomers of modafinil.
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https://hal-normandie-univ.archives-ouvertes.fr/hal-01949872
Contributor : Aurélien Lemercier <>
Submitted on : Monday, December 10, 2018 - 2:22:28 PM
Last modification on : Monday, December 2, 2019 - 2:44:06 PM

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  • HAL Id : hal-01949872, version 1

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COMUE-NORMANDIE | UNIROUEN | LABO-SMS

Citation

Olivier Neckebrock, Laurent Courvoisier, Stephanie Graf, Gilles Serrure, Gerard Coquerel, et al.. Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil. France, Patent n° : US20060135621A1. 2002. ⟨hal-01949872⟩

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