Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization

Matthias Helmreich , Claus-Peter Niesert , Daniel Cravo , Gérard Coquerel (1) , Guillaume Levilain (1) , Saoussen Wacharine-Antar , Pascal Cardinaël (1)

1 SMS - Sciences et Méthodes Séparatives

A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.

Domains: Chemical Sciences; Chemical Sciences; Material chemistry; Chemical Sciences; Cristallography; Chemical Sciences; Organic chemistry

Matthias Helmreich, Claus-Peter Niesert, Daniel Cravo, Gérard Coquerel, Guillaume Levilain, et al.. Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization. France, Patent n° : EP2411375A1. 2009. ⟨hal-01949529⟩