, The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop, Ocul Surf, vol.5, pp.75-92, 2007.
Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation, Cornea, vol.17, pp.38-56, 1998. ,
Impaired functional visual acuity of dry eye patients, Am J Ophthalmol, vol.133, pp.181-187, 2002. ,
Impact of dry eye syndrome on vision-related quality of life, Am J Ophthalmol, vol.143, pp.409-424, 2007. ,
A new approach for better comprehension of diseases of the ocular surface, J Fr Ophtalmol, vol.30, pp.239-285, 2007. ,
Animal models of dry eye: a critical assessment of opportunities and limitations, Invest Ophthalmol Vis Sci, vol.45, pp.1641-1647, 2004. ,
Apoptosis of ocular surface cells in experimentally induced dry eye, Invest Ophthalmol Vis Sci, vol.44, pp.124-133, 2003. ,
Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye, Am J Pathol, vol.166, pp.61-71, 2005. ,
Pathogenesis of Sjogren's syndrome: characteristics of different mouse models for autoimmune exocrinopathy, Clin Immunol, vol.103, pp.111-135, 2002. ,
Evaluation of novel dry eye model: preganglionic parasympathetic denervation in rabbit, Invest Ophthalmol Vis Sci, vol.48, pp.4468-75, 2007. ,
Tear film and ocular surface changes after closure of the meibomian gland orifices in the rabbit, Ophthalmology, vol.96, pp.1180-1186, 1989. ,
Natural history of disease in a rabbit model for keratoconjunctivitis sicca ,
Improvement of corneal barrier function by the P2Y(2) agonist INS365 in a rat dry eye model, Invest Ophthalmol Vis Sci, vol.192, pp.96-100, 1989. ,
Efficacy of topical nerve growth factor treatment in dogs affected by dry eye, Graefes Arch Clin Exp Ophthalmol, vol.243, pp.151-156, 2005. ,
The controlled-environment chamber: a new mouse model of dry eye, Invest Ophthalmol Vis Sci, vol.46, pp.2766-71, 2005. ,
Regulation of MMP-9 production by human corneal epithelial cells, Exp Eye Res, vol.73, pp.449-59, 2001. ,
Stimulation of matrix metalloproteinases by hyperosmolarity via a JNK pathway in human corneal epithelial cells, Invest Ophthalmol Vis Sci, vol.45, pp.4302-4313, 2004. ,
JNK and ERK MAP kinases mediate induction of IL-1beta, TNFalpha and IL-8 following hyperosmolar stress in human limbal epithelial cells, Exp Eye Res, vol.82, pp.588-96, 2006. ,
Effect of hyperosmolality on beta-defensin gene expression by human corneal epithelial cells, Cornea, vol.25, pp.1063-1071, 2006. ,
Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK, Invest Ophthalmol Vis Sci, vol.49, pp.539-588, 2008. ,
Hypertonicityinduced p38MAPK activation elicits recovery of corneal epithelial cell volume and layer integrity, J Membr Biol, vol.193, pp.1-13, 2003. ,
Fate of hypertonicity-stressed corneal epithelial cells depends on differential MAPK activation and p38MAPK/Na-K-2Cl cotransporter1 interaction, Exp Eye Res, vol.84, pp.361-72, 2007. ,
TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells, Invest Ophthalmol Vis Sci, vol.52, pp.485-93, 2011. ,
Hyperosmolarity mediated mitochondrial dysfunction requires transglutaminase-2 in human corneal epithelial cells, J Cell Physiol, vol.226, pp.693-702, 2011. ,
Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways, Cornea, vol.26, pp.452-60, 2007. ,
A rabbit dry eye model induced by topical medication of a preservative benzalkonium chloride ,
, Invest Ophthalmol Vis Sci, vol.49, pp.1850-1856, 2008.
A mouse dry eye model induced by topical administration of benzalkonium chloride, Mol Vis, vol.17, pp.257-64, 2011. ,
Quaternary ammoniums and other preservatives' contribution in oxidative stress and apoptosis on Chang conjunctival cells, Invest Ophthalmol Vis Sci, vol.42, pp.642-52, 2001. ,
Brignole-Baudouin F. In vitro comparison of cytoprotective and antioxidative effects of latanoprost, travoprost, and bimatoprost on conjunctiva-derived epithelial cells, Invest Ophthalmol Vis Sci, vol.46, pp.4594-4603, 2005. ,
Conjunctival and corneal reactions in rabbits following shortand repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride, Br J Ophthalmol, vol.92, pp.1275-82, 2008. ,
Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage, Invest Ophthalmol Vis Sci, vol.50, pp.1644-52, 2009. ,
Side effects of antiglaucomatous drugs on the ocular surface, Curr Opin Ophthalmol, vol.7, pp.80-86, 1996. ,
Conjunctival surface damage distribution in keratoconjunctivitis sicca. An impression cytology study, Ophthalmologica, vol.200, pp.170-176, 1990. ,
Quantitative analysis of conjunctival goblet cells after chronic application of topical drops, Adv Ther, vol.25, pp.743-51, 2008. ,
Prevalence of ocular surface disease in glaucoma patients, J Glaucoma, vol.17, pp.350-355, 2008. ,
Preservatives in eyedrops: the good, the bad and the ugly, Prog Retin Eye Res, vol.29, pp.312-346, 2010. ,
Prevalence of ocular symptoms and signs with preserved and preservative free glaucoma medication, Br J Ophthalmol, vol.86, pp.418-441, 2002. ,
Ocular symptoms and signs with preserved and preservative-free glaucoma medications, Eur J Ophthalmol, vol.17, pp.341-350, 2007. ,
Prevalence of ocular surface complaints in patients with glaucoma using topical intraocular pressure-lowering medications, Cornea, vol.29, pp.618-639, 2010. ,
German register for glaucoma patients with dry eye. I. Basic outcome with respect to dry eye, Graefes Arch Clin Exp Ophthalmol, vol.246, pp.1593-601, 2008. ,
Detrimental effect of preservatives in eyedrops: implications for the treatment of glaucoma, Acta Ophthalmol, vol.86, pp.716-742, 2008. ,
Tear film osmolarity in patients treated for glaucoma or ocular hypertension ,
Comparative study on the cytotoxic effects of benzalkonium chloride on the Wong-Kilbourne derivative of Chang conjunctival and IOBA-NHC cell lines, Mol Vis, vol.14, pp.394-402, 2008. ,
The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death, Immunol Today, vol.16, pp.524-532, 1995. ,
Osmolarity of tear microvolumes in keratoconjunctivitis sicca, Arch Ophthalmol, vol.96, pp.677-81, 1978. ,
Tear osmolarity in the diagnosis and management of dry eye disease, Am J Ophthalmol, vol.151, pp.792-800, 2011. ,
Adaptation by corneal epithelial cells to chronic hypertonic stress depends on upregulation of Na:K:2Cl cotransporter gene and protein expression and ion transport activity, J Membr Biol, vol.177, pp.41-50, 2000. ,
In vitro effects of preservative-free tafluprost and preserved latanoprost, travoprost, and bimatoprost in a conjunctival epithelial cell line, Curr Eye Res, vol.33, pp.303-315, 2008. ,
Hyperosmotic activation of the CD95 system, Methods Enzymol, vol.428, pp.145-60, 2007. ,
Reactive oxygen species are required for the hypothalamic osmoregulatory response, Endocrinology, vol.153, pp.1317-1346, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01542829
Effects of benzalkonium chloride on growth and survival of Chang conjunctival cells, Invest Ophthalmol Vis Sci, vol.40, pp.619-649, 1999. ,
Molecular characterization of mitochondrial apoptosis-inducing factor, Nature, vol.397, pp.441-447, 1999. ,
Apoptosis inducing factor (AIF): a phylogenetically old, caspaseindependent effector of cell death, Cell Death Differ, vol.6, pp.516-540, 1999. ,
The pathology of dry eye: the interaction between the ocular surface and lacrimal glands, Cornea, vol.17, pp.584-593, 1998. ,
A unified theory of the role of the ocular surface in dry eye, Adv Exp Med Biol, vol.438, pp.643-51, 1998. ,
The diagnosis and management of dry eye: a twenty-five-year review, Cornea, vol.19, pp.644-653, 2000. ,
Dry eye syndromes, Chem Immunol Allergy, vol.92, pp.176-84, 2007. ,
Lubricating agents differ in their protection of cultured human epithelial cells against desiccation, Med Sci Monit, vol.14, pp.12-18, 2008. ,
Hyperosmolar Stress Upregulates HLA-DR Expression in Human Conjunctival Epithelium in Dry Eye Patients and In Vitro Models, Invest Ophthalmol Vis Sci, vol.52, pp.5488-96, 2011. ,
Sjogren's syndrome: cytokine and Epstein-Barr viral gene expression within the conjunctival epithelium, Invest Ophthalmol Vis Sci, vol.35, pp.3493-504, 1994. ,
Flow cytometric analysis of inflammatory markers in conjunctival epithelial cells in patients with dry eyes, Invest Ophthalmol Vis Sci, vol.41, pp.1356-63, 2000. ,
Flow cytometric analysis of inflammatory markers in KCS: 6-month treatment with topical cyclosporin A, Invest Ophthalmol Vis Sci, vol.42, pp.90-95, 2001. ,