Expression of Serotonin 7 Receptor and Coupling of Ectopic Receptors to Protein Kinase A and Ionic Currents in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Causing Cushing’s Syndrome

Estelle Louiset (1, 2) , Vincent Contesse (3) , Lionel Groussin (4, 5, 6, 7, 8) , Dorthe Cartier (1) , Céline Duparc (2, 1) , Gaelle Barrande (9) , Jérôme Bertherat (8, 4, 5, 6, 7) , Hubert Vaudry (3) , Hervé Lefebvre (2, 1, 10)

1 DC2N - Différenciation et communication neuronale et neuroendocrine
2 DC2N - Différenciation et communication neuronale et neuroendocrine
3 Neuroendocrinologie cellulaire et moléculaire
4 EMD - [Institut Cochin] Département Endocrinologie, métabolisme, diabète (EMD)
5 Hôpital Cochin [AP-HP]
6 IFRAJ - Institut Fédératif de Recherche Alfred Jost
7 UPD5 - Université Paris Descartes - Paris 5
8 UMR_S567 / UMR 8104 - Institut Cochin
9 CHRO - Centre Hospitalier Régional d'Orléans
10 Service d'endocrinologie, diabétologie et maladies métaboliques [Rouen]

In ACTH-independent macronodular adrenal hyperplasia (AIMAH) causing Cushing's syndrome, cortisol secretion is controlled by illegitimate membrane receptors.

Domains: Life Sciences [q-bio]; Human health and pathology; Endocrinology and metabolism

Estelle Louiset, Vincent Contesse, Lionel Groussin, Dorthe Cartier, Céline Duparc, et al.. Expression of Serotonin 7 Receptor and Coupling of Ectopic Receptors to Protein Kinase A and Ionic Currents in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Causing Cushing’s Syndrome. Journal of Clinical Endocrinology and Metabolism, 2006, 91 (11), pp.4578 - 4586. ⟨10.1210/jc.2006-0538⟩. ⟨hal-01928836⟩