Crystal Structures and Phase Relationships of 2 Polymorphs of 1,4-Diazabicyclo[3.2.2]nonane-4-Carboxylic Acid 4-Bromophenyl Ester Fumarate, A Selective α-7 Nicotinic Receptor Partial Agonist

Benoît Robert (1, 2) , Marc-Antoine Perrin (2) , Maria Barrio , Josep-Lluis Tamarit (3) , Gérard Coquerel (1) , René Ceolin , Ivo Rietveld

1 SMS - Sciences et Méthodes Séparatives
2 Sanofi-Aventis R&D
3 Grup de Caracteritzacio de Materials (GCM), Departament de Fisica i Enginyeria Nuclear

Domains: Chemical Sciences; Chemical Sciences; Cristallography; Chemical Sciences; Material chemistry; Chemical Sciences; Organic chemistry; Chemical Sciences; Theoretical and/or physical chemistry; Chemical Sciences; Medicinal Chemistry

Benoît Robert, Marc-Antoine Perrin, Maria Barrio, Josep-Lluis Tamarit, Gérard Coquerel, et al.. Crystal Structures and Phase Relationships of 2 Polymorphs of 1,4-Diazabicyclo[3.2.2]nonane-4-Carboxylic Acid 4-Bromophenyl Ester Fumarate, A Selective α-7 Nicotinic Receptor Partial Agonist. Journal of Pharmaceutical Sciences, 2016, 105 (1), pp.64 - 70. ⟨10.1016/j.xphs.2015.10.015⟩. ⟨hal-01928492⟩