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Intraadrenal Corticotropin in Bilateral Macronodular Adrenal Hyperplasia

Abstract : Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing's syndrome. In this form of hyperplasia, hypersecretion of cortisol suppresses the release of corticotropin by pituitary corticotrophs, which results in low plasma corticotropin levels. Thus, the disease has been termed corticotropin-independent macronodular adrenal hyperplasia. We examined the abnormal production of corticotropin in these hyperplastic adrenal glands.
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Contributor : Estelle Louiset Connect in order to contact the contributor
Submitted on : Tuesday, October 30, 2018 - 9:19:48 AM
Last modification on : Wednesday, March 2, 2022 - 3:48:01 PM
Long-term archiving on: : Thursday, January 31, 2019 - 1:16:24 PM


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Estelle Louiset, Céline Duparc, Jacques Young, Sylvie Renouf, Milène Tetsi Nomigni, et al.. Intraadrenal Corticotropin in Bilateral Macronodular Adrenal Hyperplasia. New England Journal of Medicine, Massachusetts Medical Society, 2013, 369 (22), pp.2115 - 2125. ⟨10.1056/NEJMoa1215245⟩. ⟨hal-01908272⟩



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