Impact of Molecular Flexibility on Double Polymorphism, Solid Solutions and Chiral Discrimination during Crystallization of Diprophylline Enantiomers

Clément Brandel (1) , Youness Amharar (1) , Judith M. Rollinger (2) , Ulrich Griesser (2) , Yohann Cartigny (1) , Samuel Petit (1) , Gérard Coquerel (1)

1 SMS - Sciences et Méthodes Séparatives
2 Leopold Franzens Universität Innsbruck - University of Innsbruck

Domains: Engineering Sciences [physics]; Materials; Chemical Sciences; Inorganic chemistry; Chemical Sciences; Cristallography; Chemical Sciences; Organic chemistry

Clément Brandel, Youness Amharar, Judith M. Rollinger, Ulrich Griesser, Yohann Cartigny, et al.. Impact of Molecular Flexibility on Double Polymorphism, Solid Solutions and Chiral Discrimination during Crystallization of Diprophylline Enantiomers. Molecular Pharmaceutics, 2013, 10 (10), pp.3850 - 3861. ⟨10.1021/mp400308u⟩. ⟨hal-01907990⟩