Vitamin A prevents round spermatid nuclear damage and promotes the production of motile sperm during in vitro maturation of vitrified pre-pubertal mouse testicular tissue

L Dumont (1) , A Oblette (1) , C. Rondanino (1) , F Jumeau (1, 2) , A Bironneau (1) , D Liot (1) , V Duchesne (1) , J Wils (2) , N Rives (1, 2)

1 GQG - Gamétogenèse et Qualité du Gamète - ULR 4308
2 CHU Rouen

Does vitamin A (retinol, Rol) prevent round spermatid nuclear damage and increase the production of motile sperm during in vitro maturation of vitrified pre-pubertal mouse testicular tissue?

None.

Keywords: retinol; testis; animal model; in vitro; spermatogenesis; DNA fragmentation; vitrification; cryopreservation

Domains: Life Sciences [q-bio]; Reproductive Biology

L Dumont, A Oblette, C. Rondanino, F Jumeau, A Bironneau, et al.. Vitamin A prevents round spermatid nuclear damage and promotes the production of motile sperm during in vitro maturation of vitrified pre-pubertal mouse testicular tissue. Molecular Human Reproduction, 2016, pp.819-832. ⟨10.1093/molehr/gaw063⟩. ⟨hal-01902865⟩