Hyaluronan-based hydrogels particles prepared by crosslinking with trisodium trimetaphosphate. Synthesis and characterization - Normandie Université Accéder directement au contenu
Article Dans Une Revue Carbohydrate Polymers Année : 2004

Hyaluronan-based hydrogels particles prepared by crosslinking with trisodium trimetaphosphate. Synthesis and characterization

Résumé

Hyaluronan in an emulsion was crosslinked with trisodium trimetaphosphate to synthesise hydrogel particles. The reaction was carried out to different crosslinking densities in the presence of sodium hydroxide and sodium chloride. Swelling degrees of the particles were measured in water and in sodium chloride at different concentrations to study the effect of the crosslinking density and the effect of the ionic strength on swelling. Finally, absorption of methylene blue in the particles allowed us to show a linear relationship between crosslinking density and methylene blue absorption.

Domaines

Chimie Polymères

Dates et versions

hal-01866879 , version 1 (03-09-2018)

Identifiants

Citer

V. Dulong, S. Lack, D. Le Cerf, L. Picton, J.P. Vannier, et al.. Hyaluronan-based hydrogels particles prepared by crosslinking with trisodium trimetaphosphate. Synthesis and characterization. Carbohydrate Polymers, 2004, 57 (1), pp.1 - 6. ⟨10.1016/j.carbpol.2003.12.006⟩. ⟨hal-01866879⟩
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