Iron(II)-catalysed[2+2+2] cycloaddition for pyridine ring construction

Vincent Richard (1) , Mélinda Ipouck (1) , Delphine S. Merel (1) , Sylvain Gaillard (1) , Richard J. Whitby (2) , Bernhard Witulski (1) , Jean-Luc Renaud (1)

1 LCMT - Laboratoire de chimie moléculaire et thioorganique
2 University of Southampton

We report a new, simple and air-stable iron(II) complex pre-catalyst for the synthesis of substituted pyridines via a [2+2+2] cycloaddition between diynes and nitrile derivatives.

Domaines: Chimie

Vincent Richard, Mélinda Ipouck, Delphine S. Merel, Sylvain Gaillard, Richard J. Whitby, et al.. Iron(II)-catalysed[2+2+2] cycloaddition for pyridine ring construction. Chemical Communications, 2014, 50, pp.593-595. ⟨10.1039/c3cc47700b⟩. ⟨hal-01848075⟩