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Journal articles

An organocatalytic access to spiro[4.5]decanes and spiro[4.6]undecanes containing aminolactones and 3-aminopyrrolidines

Abstract : The organocatalyzed Mannich coupling of cyclic carboxaldehydes allowed the concise and simple preparation of spirocyclic aminolactones. Their conversion into pharmaceutically relevant spiro[4.5]cyclic and spiro[4.6]cyclic 3-aminopyrrolidines is also described.
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https://hal-normandie-univ.archives-ouvertes.fr/hal-01848013
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Submitted on : Tuesday, July 24, 2018 - 11:20:54 AM
Last modification on : Thursday, December 9, 2021 - 3:54:03 PM

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M. Cormier, A. Chardon, J. Blanchet, J. Rouden, Jacques Maddaluno, et al.. An organocatalytic access to spiro[4.5]decanes and spiro[4.6]undecanes containing aminolactones and 3-aminopyrrolidines. SYNTHESIS, Georg Thieme Verlag, 2015, 47 (17), pp.2549-2553. ⟨10.1055/s-0034-1380146⟩. ⟨hal-01848013⟩

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