Skip to Main content Skip to Navigation
Journal articles

Cell wall O-glycoproteins and N-glycoproteins: aspects of biosynthesis and function

Abstract : have contributed equally to this work. Cell wall O-glycoproteins and N-glycoproteins are two types of glycomolecules whose glycans are structurally complex. They are both assembled and modified within the endomembrane system, i.e., the endoplasmic reticulum (ER) and the Golgi apparatus, before their transport to their final locations within or outside the cell. In contrast to extensins (EXTs), the O-glycan chains of arabinogalactan proteins (AGPs) are highly heterogeneous consisting mostly of (i) a short oligo-arabinoside chain of three to four residues, and (ii) a larger β-1,3-linked galactan backbone with β-1,6-linked side chains containing galactose, arabinose and, often, fucose, rhamnose, or glucuronic acid. The fine structure of arabinogalactan chains varies between, and within plant species, and is important for the functional activities of the glycoproteins. With regards to N-glycans, ER-synthesizing events are highly conserved in all eukaryotes studied so far since they are essential for efficient protein folding. In contrast, evolutionary adaptation of N-glycan processing in the Golgi apparatus has given rise to a variety of organism-specific complex structures. Therefore, plant complex-type N-glycans contain specific glyco-epitopes such as core β,2-xylose, core a α1,3-fucose residues, and Lewis substitutions on the terminal position of the antenna. Like O-glycans, N-glycans of proteins are essential for their stability and function. Mutants affected in the glycan metabolic pathways have provided valuable information on the role of N-/O-glycoproteins in the control of growth, morphogenesis and adaptation to biotic and abiotic stresses. With regards to O-glycoproteins, only EXTs and AGPs are considered herein. The biosynthesis of these glycoproteins and functional aspects are presented and discussed in this review.
Complete list of metadatas

Cited literature [117 references]  Display  Hide  Download

https://hal-normandie-univ.archives-ouvertes.fr/hal-01842174
Contributor : Arnaud Lehner <>
Submitted on : Wednesday, July 18, 2018 - 8:30:12 AM
Last modification on : Friday, February 7, 2020 - 10:10:05 AM
Long-term archiving on: : Friday, October 19, 2018 - 5:02:03 PM

File

2014-Nguema-Ona et al-Front Pl...
Files produced by the author(s)

Identifiers

Citation

Eric Nguema-Ona, Maite Vicre-Gibouin, Maxime Gotté, Barbara Plancot, Patrice Lerouge, et al.. Cell wall O-glycoproteins and N-glycoproteins: aspects of biosynthesis and function. Frontiers in Plant Science, Frontiers, 2014, 5, pp.499. ⟨10.3389/fpls.2014.00499⟩. ⟨hal-01842174⟩

Share

Metrics

Record views

42

Files downloads

71