On the dimorphism and the pressure–temperature state diagram of racemic m-nisoldipine, a dihydropyridine calcium ion antagonist

Sur le dimorphisme et le diagramme d’état pression-température de la m-nisoldipine racémique, une dihydroyridine antagoniste

Kangli Li (1) , Gabin Gbabode (1) , Gérard Coquerel (1) , René Céolin (2) , Ivo B. Rietveld (1, 2)

1 SMS - Sciences et Méthodes Séparatives
2 UPD5 Pharmacie - Université Paris Descartes - Faculté de Pharmacie de Paris

Keywords: topological P-T diagram; thermodynamic stability; crystalline polymorphism; Topological P—T diagram; Racemic m-nisoldipine

Keywords: m-nisoldipine racémique; polymorphisme cristallin; stabilité thermodynamique; diagramme P-T topologique

Domains: Theoretical and/or physical chemistry; Material chemistry; Cristallography; Pharmaceutical sciences

Kangli Li, Gabin Gbabode, Gérard Coquerel, René Céolin, Ivo B. Rietveld. On the dimorphism and the pressure–temperature state diagram of racemic m-nisoldipine, a dihydropyridine calcium ion antagonist. Annales Pharmaceutiques Françaises, 2018, 76 (5), pp.341-347. ⟨10.1016/j.pharma.2018.03.010⟩. ⟨hal-01821720⟩