HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

Formamide Synthesis through Borinic Acid Catalysed Transamidation under Mild Conditions

Abstract : A highly efficient and mild transamidation of amides with amines co‐catalysed by borinic acid and acetic acid has been reported. A wide range of functionalised formamides was synthesized in excellent yields, including important chiral α‐amino acid derivatives, with minor racemisation being observed. Experiments suggested that the reaction rely on a cooperative catalysis involving an enhanced boron‐derived Lewis acidity rather than an improved Brønsted acidity of acetic acid.
Document type :
Journal articles
Complete list of metadata

https://hal-normandie-univ.archives-ouvertes.fr/hal-01793137
Contributor : Jérôme Blanchet Connect in order to contact the contributor
Submitted on : Wednesday, May 16, 2018 - 11:24:16 AM
Last modification on : Thursday, December 9, 2021 - 3:54:03 PM

Links full text

Identifiers

Citation

Tharwat Mohy el dine, David Evans, Jacques Rouden, Jérôme Blanchet. Formamide Synthesis through Borinic Acid Catalysed Transamidation under Mild Conditions. Chemistry - A European Journal, Wiley-VCH Verlag, 2016, 22 (17), pp.5894 - 5898. ⟨10.1002/chem.201600234⟩. ⟨hal-01793137⟩

Share

Metrics

Record views

19