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Journal articles
Monoclonal Antibodies against Human Factor VIII Molecular Neutralize Antihemophilic Factor and Ristocetin Cofactor Activities.
Abstract : A series of monoclonal antibodies have been raised against a preparation of the factor VIII/von Willebrand factor molecule. Of the seven hybridomas showing specific activity against the factor VIII molecule in a solid-phase radioimmunoassay, three (F4.55, F4.77, and F4.264) have been shown to partially inhibit ristocetin-induced platelet aggregation and two (F4.115 and F4.415) inhibit the antihemophilic activity of the factor VIII molecule. An additional monoclonal antibody was directed against a contaminant of the factor VIII preparation and is an antifibrinogen antibody.
https://hal-normandie-univ.archives-ouvertes.fr/hal-01762075
Contributor : Université Normandie Connect in order to contact the contributor
Submitted on : Monday, April 9, 2018 - 3:53:59 PM
Last modification on : Friday, October 4, 2019 - 12:05:40 PM
Contributor : Université Normandie Connect in order to contact the contributor
Submitted on : Monday, April 9, 2018 - 3:53:59 PM
Last modification on : Friday, October 4, 2019 - 12:05:40 PM
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