Abstract : A hybridoma cell line secreting a monoclonal antibody directed against human fibrinogen has been isolated. The antigenic determinant recognized is present on both the fibrinogen and fibrin molecules but is apparently absent from the D and E fragments and from fibrinopeptides A and B. The antibody seems to recognize a conformational structure present in native fibrinogen and in which several or possibly all the fibrinogen polypeptide chains may participate.
Brigitte Sola, Avner Pr, Zilber Mt, Connan F, D. Lévy. Isolation and Characterization of a Monoclonal Antibody Specific for Fibrinogen and Fibrin of Human Origin.. Thrombosis Research, Elsevier, 1983, ⟨10.1016/0049-3848(83)90219-0⟩. ⟨hal-01762072⟩