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A. We, A. Plasmid, D. David, A. Solomon, S. Ucsf et al., Spain) for help in the establishment of GFP-expressing cell lines, Dr Antonio Postigo (IDIBAPS) for the gift of the pMSCV- CA) for the gift of pD1a-GFP and pD1b-GFP plasmids, and Dr Benoît Haelewyn (CURB, Université de Caen Normandie) for advice concerning mice. We thank ICORE and Cyceron (Université de Caen Normandie) for microscopy, cytometry, and imaging facilities. The work was supported by grants from ITMO Biologie cellulaire, développement et évolution (to BS Una manera de hacer Europa " (to GR) Research in the PM laboratory is supported by the European Research Council, Ligue contre le Cancer -Comité de l'Orne (to BS), and Fondo de Investigación Sanitaria PI12/01847 and PI15/00102, European Regional Development Fund (ERDF) the Spanish Ministry of Economy and Competitiveness (SAF-SAF2013-43065), the Obra Social La Caixa-Fundaciò Josep Carreras, and The Generalitat de Catalunya (SGR330). PM is an investigator of the Spanish Cell Therapy cooperative network (TERCEL). SBo obtained a mobility grant from Cancéropôle Nord- Ouest. AE-A and CR-Z held predoctoral fellowships from the Ministerio de Educación, Cultura y Deporte and Instituto de Salud Carlos III, 2014.