, denotes residue identity; residues that are underlined indicate a cleavage-amidation recognition sequence

A. Miyata, A. Arimura, D. Dahl, N. Minamino, A. Uehara et al., Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells, Biochemical and Biophysical Research Communications, vol.164, issue.1, pp.567-574, 1989.
DOI : 10.1016/0006-291X(89)91757-9

A. Miyata, D. Dahl, L. Jiang, C. Kitada, K. Kubo et al., Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38), Biochemical and Biophysical Research Communications, vol.170, issue.2, pp.643-648
DOI : 10.1016/0006-291X(90)92140-U

A. Arimura, Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research, Regulatory Peptides, vol.37, issue.3, pp.287-303, 1992.
DOI : 10.1016/0167-0115(92)90621-Z

N. Chartrel, M. Tonon, H. Vaudry, and J. Conlon, Primary Structure of Frog Pituitary Adenylate Cyclase- Activating Polypeptide (PACAP) and Effects of Ovine PACAP on Frog Pituitary*, Endocrinology, vol.129, issue.6, pp.3367-3371, 1991.
DOI : 10.1210/endo-129-6-3367

D. Parker, I. Coe, G. Dixon, and N. Sherwood, Two salmon neuropeptides encoded by one brain cDNA are structurally related to members of the glucagon superfamily, European Journal of Biochemistry, vol.259, issue.2, pp.439-448, 1993.
DOI : 10.1016/0014-5793(84)80607-9

J. Mcrory, D. Parker, S. Ngamvongchon, and N. Sherwood, Sequence and expression of cDNA for pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH)-like peptide in catfish, Molecular and Cellular Endocrinology, vol.108, issue.1-2, pp.169-177, 1995.
DOI : 10.1016/0303-7207(94)03467-8

J. Mcrory, R. Parker, and N. Sherwood, Expression and Alternative Processing of a Chicken Gene Encoding Both Growth Hormone-Releasing Hormone and Pituitary Adenylate Cyclase-Activating Polypeptide, DNA and Cell Biology, vol.16, issue.1, pp.95-102, 1997.
DOI : 10.1089/dna.1997.16.95

J. Mcrory and N. Sherwood, Endocrinology, vol.138, issue.6, pp.2380-2390, 1997.
DOI : 10.1210/endo.138.6.5167

K. Matsuda, Y. Takei, J. Katoh, S. Shioda, A. Arimura et al., Isolation and Structural Characterization of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP)-like Peptide From the Brain of a Teleost, Stargazer, Uranoscopus japonicus, Peptides, vol.18, issue.5, pp.725-727, 1997.
DOI : 10.1016/S0196-9781(97)00122-8

S. Vigh, A. Arimura, K. Kö-ves, A. Somogyvari-vigh, J. Sitton et al., Immunohistochemical localization of the neuropeptide, pituitary adenylate cyclase activating polypeptide (PACAP), in human and primate hypothalamus, Peptides, vol.12, issue.2, pp.313-318, 1991.
DOI : 10.1016/0196-9781(91)90018-K

K. Kö-ves, A. Arimura, A. Somogyvari-vigh, S. Vigh, and J. Miller, Immunohistochemical Demonstration of a Novel Hypothalamic Peptide, Pituitary Adenylate Cyclase-Activating Polypeptide, in the Ovine Hypothalamus*, Endocrinology, vol.127, issue.1, pp.264-271, 1990.
DOI : 10.1210/endo-127-1-264

K. Kö-ves, A. Arimura, and T. Gorcs, Comparative Distribution of Immunoreactive Pituitary Adenylate Cyclase Activating Polypeptide and Vasoactive Intestinal Polypeptide in Rat Forebrain, Neuroendocrinology, vol.54, issue.2, pp.159-169
DOI : 10.1159/000125864

L. Yon, M. Feuilloley, N. Chartrel, A. Arimura, J. Conlon et al., Immunohistochemical distribution and biological activity of pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nervous system of the frogRana ridibunda, The Journal of Comparative Neurology, vol.173, issue.4, pp.485-499, 1992.
DOI : 10.1679/aohc1950.43.157

A. Gobbetti, M. Zerani, A. Miano, M. Bramucci, O. Murri et al., Presence of pituitary adenylate cyclase-activating polypeptide 38-immuno-like material in the brain and ovary of the female crested newt, Triturus carnifex: its involvement in the ovarian synthesis of prostaglandins and steroids, Journal of Endocrinology, vol.152, issue.1, pp.141-146, 1997.
DOI : 10.1677/joe.0.1520141

S. Rawlings and M. Hezareh, Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP/Vasoactive intestinal polypeptide receptors: actions on the anterior pituitary gland, Endocr Rev, vol.17, pp.4-29, 1996.
DOI : 10.1210/er.17.1.4

S. Rawlings, Pituitary adenylate cyclase-activating polypeptide regulates [Ca2+]i and electrical activity in pituitary cells through cell type-specific mechanisms, Trends in Endocrinology & Metabolism, vol.7, issue.10, pp.374-378, 1996.
DOI : 10.1016/S1043-2760(96)00187-7

F. Gracia-navarro, M. Lamacz, and M. Tonon, Pituitary adenylate cyclase-activating polypeptide stimulates calcium mobilization in amphibian pituitary cells., Endocrinology, vol.131, issue.3, pp.1069-1074
DOI : 10.1210/endo.131.3.1324148

M. Hosoya, C. Kimura, K. Ogi, S. Ohkubo, Y. Miyamoto et al., Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene, Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene, pp.199-206, 1992.
DOI : 10.1016/0167-4781(92)90488-L

U. Gubler, J. Monahan, P. Lomedico, R. Bhatt, K. Collier et al., Cloning and sequence analysis of cDNA for the precursor of human growth hormone-releasing factor, somatocrinin., Proceedings of the National Academy of Sciences, vol.80, issue.14, pp.4311-4314, 1983.
DOI : 10.1073/pnas.80.14.4311

D. Parker, M. Power, P. Swanson, J. Rivier, and N. Sherwood, Endocrinology, vol.138, issue.1, pp.413-423, 1997.
DOI : 10.1210/endo.138.1.4830

A. Martinez-fuentes, J. Gonzalez-de-aguilar, S. Lacuisse, S. Kikuyama, H. Vaudry et al., Effect of frog pituitary adenylate cyclaseactivating polypeptide (PACAP) on amphibian pituitary cells Vasoactive Intestinal Peptide, Pituitary Adenylate Cyclase-Activating Polypeptide and Related Regulatory Peptides: From Molecular Biology to Clinical Applications, World Scientific, pp.376-380, 1994.

G. Hart, H. Gowing, and J. Burrin, Effects of a novel hypothalamic peptide, pituitary adenylate cyclase-activating polypeptide, on pituitary hormone release in rats, Journal of Endocrinology, vol.134, issue.1, pp.33-41, 1992.
DOI : 10.1677/joe.0.1340033

T. Hashizume, S. Koyama, and S. Kanematsu, Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) on the Release of Growth Hormone (GH), Luteinizing Hormone (LH), and Prolactin (PRL) from Cultured Bovine Anterior Pituitary Cells In Vitro, Nihon Chikusan Gakkaiho, vol.65, issue.11, pp.993-998, 1994.
DOI : 10.2508/chikusan.65.993

B. Desai, J. Monson, J. Holdstock, S. Aylwin, J. Geddes et al., Burrin JM 1994 Effects of pituitary adenylate cyclase-activating polypeptide on hormone secretion by human pituitary adenomas in vitro, J Clin Endocrinol Metab, vol.79, pp.1771-1777

E. Donaldson, U. Fagerlund, D. Higgs, and J. Mcbride, Hormonal Enhancement of Growth, pp.456-597, 1979.
DOI : 10.1016/S1546-5098(08)60032-1

E. Mclean, E. Donaldson, H. Dye, and L. Souza, Growth acceleration of coho salmon (Oncorhynchus kisutch) following oral administration of recombinant bovine somatotropin, Aquaculture, vol.91, issue.1-2, pp.197-203, 1990.
DOI : 10.1016/0044-8486(90)90188-S

W. Clarke, S. Farmer, and K. Hartwell, Effect of teleost pituitary growth hormone on growth of Tilapia mossambica and on growth and seawater adaptation of sockeye salmon (Oncorhynchus nerka), General and Comparative Endocrinology, vol.33, issue.2, pp.174-178, 1977.
DOI : 10.1016/0016-6480(77)90241-6

T. Sakamoto, S. Mccormick, and T. Hirano, Osmoregulatory actions of growth hormone and its mode of action in salmonids: A review, Fish Physiology and Biochemistry, vol.82, issue.Serie III, pp.155-164, 1993.
DOI : 10.1507/endocrj1954.18.47

R. Borski, J. Yoshikawa, S. Madsen, R. Nishioka, C. Zabetian et al., Effects of Environmental Salinity on Pituitary Growth Hormone Content and Cell Activity in the Euryhaline Tilapia, Oreochromis mossambicus, General and Comparative Endocrinology, vol.95, issue.3, pp.483-494, 1994.
DOI : 10.1006/gcen.1994.1148

H. Singh and P. Thomas, Mechanism of Stimulatory Action of Growth Hormone on Ovarian Steroidogenesis in Spotted Seatrout, Cynoscion nebulosus, General and Comparative Endocrinology, vol.89, issue.3, pp.341-353, 1993.
DOI : 10.1006/gcen.1993.1042

G. Van-der-kraak, P. Rosenblum, and R. Peter, Growth homone-dependent potentiation of gonadotropin-stimulated steroid production by ovarian follicles of the goldfish, General and Comparative Endocrinology, vol.79, issue.2, pp.233-239, 1990.
DOI : 10.1016/0016-6480(90)90108-X

L. Gac, F. Blaise, O. Fostier, A. , L. Bail et al., Growth hormone (GH) and reproduction: a review, Fish Physiology and Biochemistry, vol.103, issue.(suppl 1), pp.219-232, 1993.
DOI : 10.1113/jphysiol.1991.sp018856

P. Peyon, S. Baloche, and E. Burzawa-gerard, Potentiating Effect of Growth Hormone on Vitellogenin Synthesis Induced by 17??-Estradiol in Primary Culture of Female Silver Eel (Anguilla anguillaL.) Hepatocytes, General and Comparative Endocrinology, vol.102, issue.2, pp.263-273, 1996.
DOI : 10.1006/gcen.1996.0068

J. Marchelidon, M. Schmitz, L. Houdebine, B. Vidal, L. Belle et al., Development of a Radioimmunoassay for European Eel Growth Hormone and Application to the Study of Silvering and Experimental Fasting, General and Comparative Endocrinology, vol.102, issue.3, pp.360-369, 1996.
DOI : 10.1006/gcen.1996.0079

R. Peter and V. Gill, A stereotaxic atlas and technique for forebrain nuclei of the goldfish,Carassius auratus, The Journal of Comparative Neurology, vol.22, issue.1, pp.69-102, 1975.
DOI : 10.1007/978-1-4899-6527-1_4

M. Fremberg, T. Van-veen, and H. Hartwig, Formaldehyde-induced fluorescence in the telencephalon and diencephalon of the eel (Anguilla anguilla L.), Cell and Tissue Research, vol.176, issue.1, pp.1-22, 1977.
DOI : 10.1007/BF00220340

O. Kah, S. Dufour, S. Baloche, and B. Breton, The GnRH systems in the brain and pituitary of normal and hCG treated European silver eels, Fish Physiology and Biochemistry, vol.81, issue.5, pp.279-284, 1989.
DOI : 10.1007/978-1-4615-9453-6_23

M. Medina, L. Belle, N. Reperant, J. Rio, J. Ward et al., An experimental study of the retinal projections of the European eel (Anguilla anguilla), carried out at the catadromic migratory silver stage, J Hirnforsch, vol.31, pp.467-480, 1990.

M. Medina, J. Reperant, S. Dufour, R. Ward, L. Belle et al., The distribution of GABA-immunoreactive neurons in the brain of the silver eel (Anguilla anguilla L.), Anat Embryol, vol.189, pp.25-39, 1994.

S. Dufour, C. Pasqualini, B. Kerdelhué, and Y. Fontaine, Presence and distribution of radioimmunoassayable LHRH in the european eel, Anguilla anguilla, Neuropeptides, vol.3, issue.2, pp.159-171, 1982.
DOI : 10.1016/0143-4179(82)90011-7

O. Lowry, A. Rosebrough, A. Farr, and R. Randall, Protein measurement with the Folin phenol reagent, J Biol Chem, vol.193, pp.265-275, 1951.

A. Laquerrière, P. Leroux, B. Gonzalez, C. Bodenant, R. Benoit et al., Distribution of somatostatin receptors in the brain of the frogRana ridibunda: Correlation with the localization of somatostatin-containing neurons, The Journal of Comparative Neurology, vol.49, issue.3, pp.451-467, 1989.
DOI : 10.1679/aohc1950.43.157

L. Yon, L. Jeandel, N. Chartrel, M. Feuilloley, J. Conlon et al., Neuroanatomical and Physiological Evidence for the Involvement of Pituitary Adenylate Cyclase-Activating Polypeptide in the Regulation of the Distal Lobe of the Frog Pituitary, Journal of Neuroendocrinology, vol.193, issue.3, pp.289-296
DOI : 10.1002/cne.903240403

M. Montero, L. Belle, N. Vidal, B. Dufour, and S. , Primary Cultures of Dispersed Pituitary Cells from Estradiol-Pretreated Female Silver Eels (Anguilla anguillaL.): Immunocytochemical Characterization of Gonadotropic Cells and Stimulation of Gonadotropin Release, General and Comparative Endocrinology, vol.104, issue.1, pp.103-115, 1996.
DOI : 10.1006/gcen.1996.0146

K. Rousseau, Y. Huang, L. Belle, N. Vidal, B. Marchelidon et al., Long-Term Inhibitory Effects of Somatostatin and Insulin-Like Growth Factor 1 on Growth Hormone Release by Serum-Free Primary Culture of Pituitary Cells from European Eel (Anguilla anguilla), Neuroendocrinology, vol.67, issue.4, pp.301-309, 1998.
DOI : 10.1159/000054327

M. Montero, B. Vidal, J. King, G. Tramu, F. Vandesande et al., Immunocytochemical localization of mammalian GnRH (gonadotropin-releasing hormone) and chicken GnRH-II in the brain of the European silver eel (Anguilla anguilla L.), Journal of Chemical Neuroanatomy, vol.7, issue.4, pp.227-241, 1994.
DOI : 10.1016/0891-0618(94)90015-9

A. Arimura, A. Somogyvari-vigh, A. Miyata, K. Mizuno, D. Coy et al., Tissue Distribution of PACAP as Determined by RIA: Highly Abundant in the Rat Brain and Testes, Endocrinology, vol.129, issue.5, pp.2787-2789, 1991.
DOI : 10.1210/endo-129-5-2787

M. Olivereau, J. Olivereau, and F. Vandesande, Localization of growth hormone-releasing factor-like immunoreactivity in the hypothalamo-hypophysial system of some teleost species, Cell and Tissue Research, vol.71, issue.1, pp.73-80, 1990.
DOI : 10.1007/BF00571432

K. Sawangjaroen and S. Anderson, Curlewis JD 1997 Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) on hormone secretion from sheep pituitary cells in vitro
DOI : 10.1046/j.1365-2826.1997.00580.x

, J Neuroendocrinol, vol.9, pp.279-286

A. Martinez-fuentes, M. Malagon, J. Castano, J. Garrido-gracia, and F. Gracia-navarro, Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP27 differentially stimulate growth hormone release and mRNA accumulation in porcine somatotropes, Life Sciences, vol.62, issue.26, pp.2379-2390, 1998.
DOI : 10.1016/S0024-3205(98)00220-3

M. Goth, C. Lyons, B. Canny, and M. Thorner, Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GHreleasing hormone stimulate GH release through distinct pituitary receptors, Endocrinology, vol.130, pp.939-944, 1992.

K. Peeters, L. Langouche, F. Vandesande, V. Darras, and L. Berghman, Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on cAMP formation and growth hormone release from chicken anterior pituitary cells, Ann NY Acad Sci

B. Canny, S. Rawlings, and D. Leong, Pituitary adenylate cyclase-activating polypeptide specifically increases cytosolic calcium ion concentration in rat gonadotropes and somatotropes., Endocrinology, vol.130, issue.1, pp.211-215, 1992.
DOI : 10.1210/endo.130.1.1727697

T. Yada and S. Vigh, Pituitary adenylate cyclase activating polypeptide (PACAP) increases cytosolic-free calcium concentration in folliculo-stellate cells and somatotropes of rat pituitary, Peptides, vol.14, issue.2, pp.235-239
DOI : 10.1016/0196-9781(93)90035-F

B. Gonzalez, M. Basille, D. Vaudry, A. Fournier, and H. Vaudry, Pituitary adenylate cyclase-activating polypeptide, Ann Endocrinol
URL : https://hal.archives-ouvertes.fr/pasteur-00819922

P. Vertongen, B. Velkeniers, E. Hooghe-peters, and P. Robberecht, Differential alternative splicing of PACAP receptor in pituitary cell subpopulations, Molecular and Cellular Endocrinology, vol.113, issue.2, pp.131-135, 1995.
DOI : 10.1016/0303-7207(95)03626-I

D. Luo, B. Mckeown, J. Rivier, and W. Vale, In vitro responses of rainbow trout (Oncorhynchus mykiss) somatotrophs to carp growth hormone-releasing factor (GRF) and somatostatin, General and Comparative Endocrinology, vol.80, issue.2, pp.288-298, 1990.
DOI : 10.1016/0016-6480(90)90173-J

J. Vaughan, J. Rivier, J. Spiess, C. Peng, J. Chang et al., Isolation and Characterization of Hypothalamic Growth-Hormone Releasing Factor from Common Carp, <i>Cyprinus carpio</i>, Neuroendocrinology, vol.56, issue.4, pp.539-549, 1992.
DOI : 10.1159/000126272