R. Silva, Myopic Maculopathy: A Review, Ophthalmologica, vol.228, issue.4, pp.197-213, 2012.
DOI : 10.1159/000339893

I. Morgan, K. Ohno-matsui, S. Saw, and . Myopia, Myopia, The Lancet, vol.379, issue.9827, pp.1739-1748, 2012.
DOI : 10.1016/S0140-6736(12)60272-4

D. Fredrick and . Myopia, Myopia, BMJ, vol.324, issue.7347, pp.1195-1199, 2002.
DOI : 10.1136/bmj.324.7347.1195

M. Zejmo, M. Formi?ska-kapu?cik, E. Pieczara, E. Filipek, E. Mrukwa-kominek et al., Etiopathogenesis and management of high-degree myopia. Part I, Med Sci Monit Int Med J Exp Clin Res, vol.15, pp.199-202, 2009.

D. Flitcroft, Is myopia a failure of homeostasis? Exp Eye Res, pp.16-24, 2013.

F. Hawthorne and T. Young, Genetic contributions to myopic refractive error: Insights from human studies and supporting evidence from animal models, Experimental Eye Research, vol.114, pp.141-149, 2013.
DOI : 10.1016/j.exer.2012.12.015

W. Meng, J. Butterworth, F. Malecaze, and P. Calvas, Axial Length of Myopia: A Review of Current Research, Ophthalmologica, vol.225, issue.3, pp.127-134, 2011.
DOI : 10.1159/000317072

T. Lai, D. Fan, W. Lai, and D. Lam, Peripheral and posterior pole retinal lesions in association with high myopia: a cross-sectional community-based study in Hong Kong, Eye, vol.91, issue.2, pp.209-213, 2008.
DOI : 10.1038/sj.eye.6702573

D. Mitry and H. Zambarakji, Recent trends in the management of maculopathy secondary to pathological myopia, Graefe's Archive for Clinical and Experimental Ophthalmology, vol.31, issue.4, pp.3-13, 2012.
DOI : 10.1007/s00417-011-1889-0

M. Pardue, R. Stone, and P. Iuvone, Investigating mechanisms of myopia in mice, Experimental Eye Research, vol.114, pp.96-105, 2013.
DOI : 10.1016/j.exer.2012.12.014

S. Kantarci, L. Gazali, R. Hill, D. Donnai, G. Black et al., Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes, Nature Genetics, vol.162, issue.8, pp.957-959, 2007.
DOI : 10.1038/ng2063

I. Schrauwen, M. Sommen, C. Claes, J. Pinner, M. Flaherty et al., Broadening the phenotype of LRP2 mutations: a new mutation in LRP2 causes a predominantly ocular phenotype suggestive of Stickler syndrome, Clinical Genetics, vol.39, issue.3, pp.282-286, 2014.
DOI : 10.1111/cge.12265

K. Veth, J. Willer, R. Collery, M. Gray, G. Willer et al., Mutations in Zebrafish lrp2 Result in Adult-Onset Ocular Pathogenesis That Models Myopia and Other Risk Factors for Glaucoma, PLoS Genetics, vol.13, issue.2, p.21379331, 2011.
DOI : 10.1371/journal.pgen.1001310.s004

R. Collery, K. Veth, A. Dubis, J. Carroll, and B. Link, Rapid, Accurate, and Non-Invasive Measurement of Zebrafish Axial Length and Other Eye Dimensions Using SD-OCT Allows Longitudinal Analysis of Myopia and Emmetropization, PLoS ONE, vol.102, issue.10, p.25334040, 2014.
DOI : 10.1371/journal.pone.0110699.s003

J. Sivak, The role of the lens in refractive development of the eye: Animal models of ametropia, Experimental Eye Research, vol.87, issue.1, p.18405895, 2008.
DOI : 10.1016/j.exer.2008.03.001

R. Spoelgen, A. Hammes, U. Anzenberger, D. Zechner, O. Andersen et al., LRP2/megalin is required for patterning of the ventral telencephalon, Development, vol.132, issue.2, pp.405-414, 2005.
DOI : 10.1242/dev.01580

S. Amsellem, J. Gburek, G. Hamard, R. Nielsen, T. Willnow et al., Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule, Journal of the American Society of Nephrology, vol.21, issue.11, pp.1859-1867, 2010.
DOI : 10.1681/ASN.2010050492

T. Storm, S. Heegaard, E. Christensen, and R. Nielsen, Megalin???deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice, Cell and Tissue Research, vol.110, issue.1, pp.99-107, 2014.
DOI : 10.1007/s00441-014-1919-4

J. Leheste, F. Melsen, M. Wellner, P. Jansen, U. Schlichting et al., Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect, The FASEB Journal, vol.17, pp.247-249, 2003.
DOI : 10.1096/fj.02-0578fje

J. Hébert and S. Mcconnell, Targeting of cre to the Foxg1 (BF-1) Locus Mediates loxP Recombination in the Telencephalon and Other Developing Head Structures, Developmental Biology, vol.222, issue.2, pp.296-306, 2000.
DOI : 10.1006/dbio.2000.9732

J. Rada, S. Shelton, and T. Norton, The sclera and myopia, Experimental Eye Research, vol.82, issue.2, pp.185-200, 2006.
DOI : 10.1016/j.exer.2005.08.009

A. Christ, A. Christa, E. Kur, O. Lioubinski, S. Bachmann et al., LRP2 Is an Auxiliary SHH Receptor Required to Condition the Forebrain Ventral Midline for Inductive Signals, Developmental Cell, vol.22, issue.2, pp.268-278, 2012.
DOI : 10.1016/j.devcel.2011.11.023

O. Cases, A. Perea-gomez, D. Aguiar, A. Nykjaer, S. Amsellem et al., Cubilin, a High Affinity Receptor for Fibroblast Growth Factor 8, Is Required for Cell Survival in the Developing Vertebrate Head, Journal of Biological Chemistry, vol.288, issue.23, pp.16655-16670, 2013.
DOI : 10.1074/jbc.M113.451070

URL : https://hal.archives-ouvertes.fr/hal-00850741

M. Ortega, O. Cases, P. Merchán, R. Kozyraki, D. Clemente et al., Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development, Glia, vol.25, issue.6, pp.851-866, 2012.
DOI : 10.1002/glia.22316

T. Tkatchenko, Y. Shen, and A. Tkatchenko, Analysis of Postnatal Eye Development in the Mouse with High-Resolution Small Animal Magnetic Resonance Imaging, Investigative Opthalmology & Visual Science, vol.51, issue.1, 2010.
DOI : 10.1167/iovs.08-2767

J. Vongphanit, P. Mitchell, and J. Wang, Prevalence and progression of myopic retinopathy in an older population, Ophthalmology, vol.109, issue.4, pp.704-711, 2002.
DOI : 10.1016/S0161-6420(01)01024-7

P. Ouyang, X. Duan, and X. Zhu, Diagnosis and treatment of myopic traction maculopathy, Int J Ophthalmol, vol.5, pp.754-758, 2012.

N. Patel, T. Hejkal, A. Katz, and E. Margalit, Ocular Manifestations of Donnai-Barrow Syndrome, Journal of Child Neurology, vol.78, issue.4, pp.462-464, 2007.
DOI : 10.1177/0883073807301933

A. Bansal and G. Hubbard, PERIPHERAL RETINAL FINDINGS IN HIGHLY MYOPIC CHILDREN ???10 YEARS OF AGE, Retina, vol.30, pp.15-19, 2010.
DOI : 10.1097/IAE.0b013e3181cf5c80

R. Young, Cell death during differentiation of the retina in the mouse, The Journal of Comparative Neurology, vol.81, issue.3, pp.362-373, 1984.
DOI : 10.1002/cne.902290307

Y. Chen, O. Sawada, H. Kohno, Y. Le, C. Subauste et al., Autophagy Protects the Retina from Light-induced Degeneration, Journal of Biological Chemistry, vol.288, issue.11, pp.7506-7518, 2013.
DOI : 10.1074/jbc.M112.439935

N. Mcbrien, Regulation of scleral metabolism in myopia and the role of transforming growth factor-beta, Experimental Eye Research, vol.114, pp.128-140, 2013.
DOI : 10.1016/j.exer.2013.01.014

B. Curtin, T. Iwamoto, and D. Renaldo, Normal and Staphylomatous Sclera of High Myopia, Archives of Ophthalmology, vol.97, issue.5, pp.912-915, 1979.
DOI : 10.1001/archopht.1979.01020010470017

G. Zheng, D. Bachinsky, I. Stamenkovic, D. Strickland, D. Brown et al., Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP)., Journal of Histochemistry & Cytochemistry, vol.42, issue.4, pp.531-542, 1994.
DOI : 10.1177/42.4.7510321

A. Bento-abreu, A. Velasco, E. Polo-hernández, P. Pérez-reyes, A. Tabernero et al., Megalin is a receptor for albumin in astrocytes and is required for the synthesis of the neurotrophic factor oleic acid, Journal of Neurochemistry, vol.93, issue.3, pp.1149-1159, 2008.
DOI : 10.1111/j.1471-4159.2008.05462.x

A. Nykjaer, D. Dragun, D. Walther, H. Vorum, C. Jacobsen et al., An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3, Cell, vol.96, issue.4, pp.507-515, 1999.
DOI : 10.1016/S0092-8674(00)80655-8

E. Kur, C. A. Veth, K. Gajera, C. Andrade-navarro, M. Zhang et al., Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development, Developmental Dynamics, vol.488, issue.6, pp.1567-1577, 2011.
DOI : 10.1002/dvdy.22624

J. Graw, . Eye, and . Development, Eye Development, Curr Top Dev Biol, vol.90, pp.343-386, 2010.
DOI : 10.1016/S0070-2153(10)90010-0

Y. Chai, X. Jiang, Y. Ito, P. Bringas, J. Han et al., Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis, Dev Camb Engl, vol.127, pp.1671-1679, 2000.

L. Zhuo, M. Theis, I. Alvarez-maya, M. Brenner, K. Willecke et al., hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo, genesis, vol.12, issue.2, pp.85-94, 2000.
DOI : 10.1002/gene.10008

M. Paques, J. Guyomard, M. Simonutti, M. Roux, S. Picaud et al., Panretinal, High-Resolution Color Photography of the Mouse Fundus, Investigative Opthalmology & Visual Science, vol.48, issue.6, pp.2769-2774, 2007.
DOI : 10.1167/iovs.06-1099